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KMID : 0355620000260050437
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Journal of Korean Association of Oral and Maxillofacial Surgeons
2000 Volume.26 No. 5 p.437 ~ p.445
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COMPARATIVE STUDY OF WOUND HEALING FOLLOWING PARTIAL GLOSSECTOMY OF RAT TOGUE USING CO2 LASER AND SCALPEL
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장재필/Jae Pil Jang
김경욱/이재훈/김창진/Kyung Wook Kim/Jae Hoon Lee/Chang Jin Kim
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Abstract
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Object
This study is focused on the comparison between CO2 laser and scalpel by examining the overal process of wound healing after partial glossectomy of rats so that the result from the research could be easily applied to actual clinical
environment.
Method and Material
In this research, 2㎜ defect was formed on both lateral borders of the tongue of rats by using CO2 laser and scalpel respectively. 4rats were sacrified each time on the 1st, 2nd, 4th, 7th, 14th and 21th day according to a general
method.
After fabricating 5㎛ paraffin specimen, H&E staining and MT staining were performed.
Results
Compared to scalpel, wound healing by CO2 laser leads to a earlier initiation of vascular proliferation and re-epithelization. Therefore, some influence is exerted on the early stage of wound healing. However, the two methods seem to
undergo
the similar healing process.
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KEYWORD
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